Comparison of Microencapsulation by Emulsion-Solvent Extraction/ Evaporation Technique Using Derivatives Cellulose and Acrylate-Methacrylate Copolymer as Carriers

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Comparison of Microencapsulation by Emulsion-Solvent Extraction/Evaporation Technique Using Derivatives Cellulose and Acrylate-Methacrylate Copolymer as Carriers

BACKGROUND Microencapsulation is a useful method to prolong a drug release from dosage forms and to reduce its adverse effect (1) among various available methods. The microencapsulation of hydrophilic active ingredients requires the use of a polar dispersing phase such as a mineral oil. Acetone/paraffin systems are conventionally used. OBJECTIVES The current study aimed to investigate two dif...

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comparison of microencapsulation by emulsion-solvent extraction/evaporation technique using derivatives cellulose and acrylate-methacrylate copolymer as carriers

background microencapsulation is a useful method to prolong a drug release from dosage forms and to reduce its adverse effect (1) among various available methods. the microencapsulation of hydrophilic active ingredients requires the use of a polar dispersing phase such as a mineral oil. acetone/paraffin systems are conventionally used. objectives the current study aimed to investigate two diffe...

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Microencapsulation of Zidovudine by Double Emulsion Solvent Diffusion Technique using Ethylcellulose

Zidovudine-ethylcellulose microspheres were prepared by water-in-oil-in-oil double emulsion solvent diffusion method. Spherical free flowing microspheres having an entrapment efficiency of 32-54% were obtained. The effect of polymer-drug ratio, surfactant concentration for secondary emulsification process, volume of processing medium and stirring speed of secondary emulsification process was ev...

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ژورنال

عنوان ژورنال: Jundishapur Journal of Natural Pharmaceutical Products

سال: 2012

ISSN: 1735-7780,2228-7876

DOI: 10.5812/jjnpp.3986